University of California, Riverside

Bourns College of Engineering

Kaustabh Ghosh

Faculty Profile

Faculty Profile

Kaustabh Ghosh

Assistant Professor of Bioengineering
Kaustabh Ghosh

Ph.D. Biomedical Engineering
State University of New York, Stony Brook, 2006

Materials Science and Engineering 207
University of California, Riverside
Riverside, CA 92521

Telephone: 951-827-4203
Fax: 951-827-6416
Personal Webpage
Prior Institutions: Children's Hospital Boston and Harvard Medical School


Kaustabh Ghosh is an Assistant Professor in the Department of Bioengineering at UC, Riverside. He is an interdisciplinary biomedical scientist and engineer with research interest in endothelial mechanobiology, vascular inflammation, and nanomedicine. Prior to joining UCR, he was a postdoctoral fellow in Don Ingber’s lab in the Vascular Biology Program at Children’s Hospital Boston and Harvard Medical School. He received his Ph.D. in Biomedical Engineering from SUNY Stony Brook in 2006, where he worked in the laboratories of Richard Clark and Miriam Rafailovich on the development of polymeric hydrogels for wound repair. He obtained his undergraduate degree in Chemical Engineering from National Institute of Technology, Warangal, India in 2001. 


  • Ph.D. Biomedical Engineering, State University of New York (SUNY), Stony Brook, 2006
  • M.S. Biomedical Engineering, State University of New York (SUNY), Stony Brook, 2002
  • B.Tech Chemical Engineering, National Institute of Technology, Warangal, India, 2001


  • 2016, Outstanding Engineering Educator Award, Orange County Engineering Council
  • 2014, Hellman Fellowship
  • 2013, University of California Regents Faculty Fellowship
  • 2008, Postdoctoral Training Grant, NIH/NIBIB (T32) Interdisciplinary Research Training Program
  • 2006, President’s Award to Distinguished Doctoral Students, SUNY Stony Brook
  • 2004, Graduate Student Scholarship, New Jersey Center for Biomaterials
  • 2004, Outstanding Mentor Award, Siemens Foundation
  • 1999-2001, Undergraduate Merit Scholarship, National Institute of Technology, Warangal, INDIA

Research Areas

Research in the Ghosh lab aims to integrate the principles of endothelial mechanobiology and nanomedicine to tackle chronic vascular inflammation. Specifically, his lab works at the interface of basic and applied science to understand how vascular stiffness regulates inflammation in diabetic retinopathy, age-related macular degeneration, and cardiovascular diseases. Simultaneously, they are developing ‘site-targeting’ nanotherapeutic approaches that can selectively deliver therapeutic agents (pharmacological drugs, RNA, plasmids) to sites of vascular inflammation and achieve localized vascular normalization. To successfully pursue these goals, the Ghosh lab integrates the multidisciplinary principles and techniques related to vascular biology, inflammation, mechanobiology, bioengineering, and nanotechnology. By identifying a new class of anti-inflammatory drugs and delivering them directly to the target site, Dr. Ghosh’s research ultimately aims to develop superior therapies for inflammation-mediated vascular diseases. 

Selected Publications

  • Scott HA, Quach B, Yang X, Ardekani S, Cabrera A, Wilson R, Messaoudi-Powers I, Ghosh K. Matrix stiffness exerts biphasic control over monocyte-endothelial adhesion via Rho-mediated ICAM-1 clustering. Integrative Biology. 2016; 8: 869-878

  • Yang X, Scott HA, Monickaraj F, Xu J, Ardekani S, Nitta CF, Cabrera A, McGuire PG, Mohideen U, Das A, Ghosh K. Basement membrane stiffening promotes retinal endothelial activation associated with diabetes. The FASEB Journal. 2016; 30(2):601-11

  • Ardekani S, Scott HA, Gupta S, Eum S, Yang X, Brunelle A, Wilson S, Mohideen U, Ghosh K. Novel Nanoliposomal Nitroglycerin Exerts Potent Anti-Inflammatory Effects. Scientific Reports 2015; Nov 20: 5, 16258.

  • Adini I, Ghosh K, Adini A, Chi ZL, Yoshimura T, Benny O, Connor KM, Rogers MS, Bazinet L, Birsner AE, Bielenberg DR, D'Amato RJ. Melanocyte-secreted fibromodulin promotes an angiogenic microenvironment. Journal of Clinical Investigation 2014; 124(1):425-36.

  • Ghosh K, Kanapathipillai M, Korin N, McCarthy J, Ingber DE. Polymeric nanomaterials for islet targeting and immunotherapeutic delivery. Nano Letters. 2012; 12(1):203-8.

  • Ghosh K, Thodeti CK, Dudley AC, Mammoto A, Klagsbrun M, Ingber DE. Tumor-derived endothelial cells exhibit aberrant Rho-mediated mechanosensing and abnormal angiogenesis in vitro. Proceedings of the National Academy of Sciences USA. 2008; 105(32):11305-11310.

  • Ghosh K, Pan Z, Guan E, Ge S, Liu Y, Nakamura T, Ren X-D, Rafailovich M, Clark RAF. Cell adaptation to a physiologically relevant ECM mimic with different viscoelastic properties. Biomaterials. 2007; 28(4):671-679

  • Ghosh K and Ingber DE. Micromechanical control of cell and tissue development. Implications for tissue engineering. Advanced Drug Delivery Reviews. 2007; 59(13):1306-1318.

    For complete list of Dr. Ghosh’s publications, visit his Bibliography

More Information 

General Campus Information

University of California, Riverside
900 University Ave.
Riverside, CA 92521
Tel: (951) 827-1012

College Information

Bourns College of Engineering
446 Winston Chung Hall

Tel: (951) 827-5190
Fax: (951) 827-3188