University of California, Riverside

Bourns College of Engineering



William H. Grover


Faculty Profile

Faculty Profile

William H. Grover

Assistant Professor of Bioengineering
William H. Grover

Ph.D. Chemistry
University of California, Berkeley, 2006

Materials Science & Engineering 219
University of California, Riverside
Riverside, CA 92521

Telephone: 951-827-4311
Facsimile: 951-827-6416
E-mail: wgrover@engr.ucr.edu

Lab Website

Former Institution: Massachusetts Institute

Biography

William H. Grover is an Assistant Professor in the Department of Bioengineering at the University of California, Riverside. Prior to joining UCR, Dr. Grover received his postdoctoral training in the Biological Engineering Division at Massachusetts Institute of Technology. In Prof. Scott Manalis' group at MIT, Dr. Grover used the group's microfluidic mass sensors to make the first precision measurements of the density of single living cells. Dr. Grover obtained his Ph.D. in Chemistry at the University of California, Berkeley. In Prof. Richard Mathies' group at UC Berkeley, Dr. Grover developed microfluidic "processors" that bridged the chemical, biological, and computational sciences. A native of Tennessee, Dr. Grover received his B.S. in Chemistry at the University of Tennessee, Knoxville.

Degrees

  • Ph.D. in Chemistry with Prof. Richard A. Mathies, University of California, Berkeley, 2006
  • B.S. in Chemistry, University of Tennessee, Knoxville, 1999

Research Areas

The Grover Lab develops precision tools for measuring and exploiting differences in the fundamental physical properties of micron-scale objects like cells, microorganisms, and particles. We make precision measurements of properties like mass, volume, and their ratio, density. These physical properties provide useful information about the biological state of a cell or organism, or the chemical composition of a particle. Since all objects have these fundamental physical properties, our research has applications in fields as diverse as cell biology, materials science, forensics, environmental science, and pharmacology.

Selected Publications

  • William H. Grover, Andrea K. Bryan, Monica Diez-Silva, Subra Suresh, John M. Higgins, and Scott R. Manalis. Measuring single-cell density. Proceedings of the National Academy of Sciences of the USA 108 (27), 10992–10996 (2011).
  • Michel Godin, Francisco Feijo Delgado, Sungmin Son, William H. Grover, Andrea K. Bryan, Amit Tzur, Paul Jorgensen, Kris Payer, Alan D. Grossman, Marc W. Kirschner, and Scott R. Manalis. Using buoyant mass to measure the growth of single cells. Nature Methods 7 (5), 387–390 (2010).
  • William H. Grover, Marcio G. von Muhlen, and Scott R. Manalis. Teflon films for chemically-inert microfluidic valves and pumps. Lab on a Chip 8, 913–918 (2008).
  • Sungmin Son, William H. Grover, Thomas P. Burg, and Scott R. Manalis. Suspended microchannel resonators for ultra-low volume universal detection. Analytical Chemistry 80 (12), 4757–4760 (2008).
  • Erik C. Jensen, William H. Grover, and Richard A. Mathies. Micropneumatic digital logic structures for integrated microdevice computation and control. Journal of Microelectromechanical Systems 16 (6), 1378–1385 (2007).
  • William H. Grover, Robin H. C. Ivester, Erik C. Jensen and Richard A. Mathies. Development and multiplexed control of latching pneumatic valves using microfluidic logical structures. Lab on a Chip 6, 623–631 (2006).
  • Brian M. Paegel, William H. Grover, Alison M. Skelley, Richard A. Mathies, and Gerald F. Joyce. Microfluidic serial dilution circuit. Analytical Chemistry 78 (21), 7522–7527 (2006).
  • William H. Grover and Richard A. Mathies. An integrated microfluidic processor for single nucleotide polymorphism-based DNA computing. Lab on a Chip 5, 1033–1040 (2005).
  • Alison M. Skelley, James R. Scherer, Andrew D. Aubrey, William H. Grover, Robin H. C. Ivester, Pascale Ehrenfreund, Frank J. Grunthaner, Jeffrey L. Bada, and Richard A. Mathies. Development and evaluation of a microdevice for amino acid biomarker detection and analysis on Mars. Proceedings of the National Academy of Sciences of the USA 102 (4), 1041–1046 (2005).
  • William H. Grover, Alison M. Skelley, Chung N. Liu, Eric T. Lagally and Richard A. Mathies. Monolithic membrane valves and diaphragm pumps for practical large-scale integration into glass microfluidic devices. Sensors and Actuators B 89 (3), 315–323 (2003).

More Information 

General Campus Information

University of California, Riverside
900 University Ave.
Riverside, CA 92521
Tel: (951) 827-1012

College Information

Bourns College of Engineering
446 Winston Chung Hall

Tel: (951) 827-5190
Fax: (951) 827-3188
E-mail: collegeinfo@engr.ucr.edu

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