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Research Group of
Professor Victor G. J. Rodgers
Department of Bioengineering
University of California, Riverside
victor.rodgers@ucr.edu

© 2007 V. G. J. Rodgers



Membrane Separations of Binary Proteins

Alumni:
Dr. Sheldon Oppenheim,
Ms. Sylvana Derjani

GRA: Yiheng Wang

bioseparationsProtein ultrafiltration has been the dominant area of our research. Our research group has addressed a number of separations issues. We pioneered the novel methodology of high frequency transmembrane pressure pulsing to address the problem of membrane fouling, is now universally adopted, we developed techniques for investigating membrane fouling using EPR spectroscopy and we are now using molecular modeling to address electrostatic interactions of binary protein separations.

Much of this work was supported by USDA and NSF.

 
 

Related Publications

  1. Wang, Y., and Rodgers, V.G.J., “Free-Solvent Model Shows Osmotic Pressure is the Dominant Factor in Limiting Flux During Protein Ultrafiltration”, Journal of Membrane Science, 320 335-343, (2008).
  2. Wang, Y.,and Rodgers, V.G.J., “Ultrafiltration and Nanofiltration Membranes”, for the Encyclopedia of Surface and Colloid Science, Second Edition; Taylor & Francis: New York, 8, 6394 – 6415 (2006).
  3. Derjani-Bayeh, S., and Rodgers, V.G.J., “Sieving Variations Due to the Choice in Pore Size Distribution Model”, Journal of Membrane Science, 209(1) 1-17 (2002).
  4. Jones, W., Valentine, R., and Rodgers, V.G.J., “Removal of Suspended Clay from Water using Transmembrane Pressure Pulsed Microfiltration”, Journal of Membrane Science, 157, 199-210 (1999).
  5. Oppenheim, S. F., Phillips, C., and Rodgers, V.G.J., “Analysis of Initial Protein Surface Coverage on Fouled Ultrafiltration Membranes”, Journal of Colloid and Interface Science, 184, 639-651 (1996).
  6. Oppenheim, S.F., Rich, J. O., Buettner, G., and Rodgers, V.G.J., “Protein Structure Change on Adherence to Ultrafiltration Membranes. An Examination by Electron Paramagnetic Resonance Spectroscopy”, Journal of Colloid and Interface Science, 183, 274-279 (1996).
  7. Wilharm, C., and Rodgers, V.G.J., “Significance of Duration and Amplitude in Transmembrane Pressure Pulsing”, Journal of Membrane Science, 121(2) 217-228 (1996).
  8. Oppenheim, S. F., Buettner, G. R., and Rodgers, V.G.J., “Relationship of Rotational Correlation Time from EPR Spectroscopy and Protein-Membrane Interaction”, Journal of Membrane Science, 118, 133-139 (1996).
  9. Rodgers, V.G.J., Oppenheim, S. F., and Datta, R., “Correlation of Permeability and Solute Uptake in Membranes of Arbitrary Pore Morphology”, AIChE Journal, 41(7), 1826-1829 (1995).
  10. Oppenheim, S. F., Buettner, G., Dordick, J., and Rodgers, V.G.J., “Applying Electron Paramagnetic Resonance (EPR) Spectroscopy to the Study of Fouling in Protein Ultrafiltration”, Journal of Membrane Science, 96 289-297 (1994).
  11. Nel, R. G., Oppenheim, S. F. and Rodgers, V.G.J., “Solution Properties Effects on Solute and Permeate Flux in BSA-IgG Ultrafiltration”, Biotechnology Progress, 10(5), 539-542 (1994).
  12. Rodgers, V.G.J., and Miller, K., “Analysis of Steric Hindrance Reduction in Pulsed Protein Ultrafiltration”, Journal of Membrane Science, 85, 39-58 (1993).
  13. Rodgers, V.G.J., and Sparks, R. E., “Effect of Solution Properties on Polarization Redevelopment and Flux in Pressure Pulsed Ultrafiltration”, Journal of Membrane Science, 78, 163 - 180 (1993).
  14. Miller, K., Weitzel, S., and Rodgers, V.G.J., “Reduction of Membrane Fouling in the Presence of High Polarization Resistance”, Journal of Membrane Science, 76, 77 - 83 (1993).
  15. Rodgers, V.G.J., and Sparks, R. E., “Effect of Transmembrane Pressure Pulsing on Concentration Polarization”, Journal of Membrane Science, 68, 149 - 168, (1992).
  16. Rodgers, V.G.J., and Sparks, R. E., “Reduction of Membrane Fouling in the Ultrafiltration of Binary Protein Mixtures”, AIChE Journal, 37(10), 1517 - 1528 (1991).
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